Research Profile: Protein conjugates pick polymer phase
نویسندگان
چکیده
منابع مشابه
Synthetic approach to homodimeric protein-polymer conjugates.
Synthesis of well-defined homodimeric protein-polymer conjugates using RAFT polymerization is described.
متن کاملDesign of Self-Assembling Protein-Polymer Conjugates.
Protein-polymer conjugates are of particular interest for nanobiotechnology applications because of the various and complementary roles that each component may play in composite hybrid-materials. This chapter focuses on the design principles and applications of self-assembling protein-polymer conjugate materials. We address the general design methodology, from both synthetic and genetic perspec...
متن کاملCovalent polymer-drug conjugates.
In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups). Advantages and limitations of these types of DDS are discussed through representative examples of polymer-drugs and...
متن کاملNovel enzyme-polymer conjugates for biotechnological applications
In the present research, a rapid, simple and efficient chemoselective method for the site-directed incorporation of tailor-made polymers into protein to create biocatalysts with excellent properties for pharmaceutical industrial purpose has been performed. First we focused on the protein engineering of the Geobacillus thermocatenulatus lipase 2 (BTL2) to replace the two cysteines (Cys65, Cys296...
متن کاملElectroactive polymer-peptide conjugates for adhesive biointerfaces.
Electroactive polymer-peptide conjugates have been synthesized by combining poly(3,4-ethylenedioxythiophene), a polythiophene derivative with outstanding properties, and an Arg-Gly-Asp (RGD)-based peptide in which Gly has been replaced by an exotic amino acid bearing a 3,4-ethylenedioxythiophene ring in the side chain. The incorporation of the peptide at the ends of preformed PEDOT chains has b...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2006
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac0693666